Benzene, 1-fluoro-4-[2-(trimethylsilyl)ethynyl]-
(4-Fluorophenylethynyl)trimethylsilane
CAS: 130995-12-9
Molecular Formula: C11H13FSi
Benzene, 1-fluoro-4-[2-(trimethylsilyl)ethynyl]- - Names and Identifiers
| Name | (4-Fluorophenylethynyl)trimethylsilane |
| Synonyms | (4-Fluorophenylethynyl)trimethylsilane 2-(4-fluorophenyl)ethynyl-trimethylsilane 1-Fluoro-4-[2-(trimethylsilyl)ethynyl]benzene Benzene, 1-fluoro-4-[2-(trimethylsilyl)ethynyl]- |
| CAS | 130995-12-9 |
| InChI | InChI=1/C11H13FSi/c1-13(2,3)9-8-10-4-6-11(12)7-5-10/h4-7H,1-3H3 |
Benzene, 1-fluoro-4-[2-(trimethylsilyl)ethynyl]- - Physico-chemical Properties
| Molecular Formula | C11H13FSi |
| Molar Mass | 192.3 |
| Density | 0.948g/mLat 25°C(lit.) |
| Boling Point | 40°C0.1mm Hg(lit.) |
| Flash Point | 195°F |
| Vapor Presure | 0.449mmHg at 25°C |
| Appearance | Liquid |
| Color | Colorless |
| Refractive Index | n20/D 1.5090(lit.) |
Benzene, 1-fluoro-4-[2-(trimethylsilyl)ethynyl]- - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
Benzene, 1-fluoro-4-[2-(trimethylsilyl)ethynyl]- - Introduction
4-Fluorophenylacetylene trimethylsilane ("fluorophenylacetylene trimethylsilane") is an organosilicon compound with a chemical formula of C10H11F-Si and a molecular weight of 188.28g/mol.
In terms of properties, 4-fluorophenylacetylene trimethylsilane is a colorless to pale yellow liquid with a special aromatic odor. It can react with acids and bases, and is readily soluble in organic solvents such as diethyl ether and dichloromethane.
This compound is mainly used as a reagent or catalyst in reactions in organic synthesis. It can participate in the functionalization reactions of C- H and C- C bonds, such as amination, ammonia hybridization and mutual change. It is also widely used in the synthesis of organometallic complexes, aromatic sulfides and polysubstituted acetylene.
In the preparation method, 4-fluorophenylacetylene trimethylsilane can usually be prepared by reacting 4-fluorophenylacetylene with trimethylchlorosilane under the protection of inert gas at low temperature.
Regarding safety information, 4-fluorophenylacetylene trimethylsilane is an organic compound, and it is necessary to pay attention to its protective measures during operation. It is irritating to the skin and eyes and direct contact should be avoided. Ensure good ventilation during operation and wear appropriate personal protective equipment such as chemical gloves and goggles. In addition, it should be kept away from fire and oxidizing agents and stored in a dry, cool place. During use, please follow the correct experimental practice.
In terms of properties, 4-fluorophenylacetylene trimethylsilane is a colorless to pale yellow liquid with a special aromatic odor. It can react with acids and bases, and is readily soluble in organic solvents such as diethyl ether and dichloromethane.
This compound is mainly used as a reagent or catalyst in reactions in organic synthesis. It can participate in the functionalization reactions of C- H and C- C bonds, such as amination, ammonia hybridization and mutual change. It is also widely used in the synthesis of organometallic complexes, aromatic sulfides and polysubstituted acetylene.
In the preparation method, 4-fluorophenylacetylene trimethylsilane can usually be prepared by reacting 4-fluorophenylacetylene with trimethylchlorosilane under the protection of inert gas at low temperature.
Regarding safety information, 4-fluorophenylacetylene trimethylsilane is an organic compound, and it is necessary to pay attention to its protective measures during operation. It is irritating to the skin and eyes and direct contact should be avoided. Ensure good ventilation during operation and wear appropriate personal protective equipment such as chemical gloves and goggles. In addition, it should be kept away from fire and oxidizing agents and stored in a dry, cool place. During use, please follow the correct experimental practice.
Last Update：2024-04-10 22:30:50
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